Document Detail

Chronic stable asthma and the normal arterial pressure of carbon dioxide in hypoxia.
MedLine Citation:
PMID:  6775747     Owner:  NLM     Status:  MEDLINE    
Arterial blood-gas tensions, pH, and peak expiratory flow rate were measured in 29 patients with chronic asthma in a stable state. The hypoxia in these patients was found to be comparable with the hypoxia seen in normal subjects at high altitude in its effects on arterial pressure of carbon dioxide (PaCO2). These results suggest that in patients with asthma the PaCO2 taken as normal should be related to the arterial oxygen tension. Any increase in the observed value compared with this predicted value indicates impaired respiratory control. This may well help in assessing the patients at greatest risk during an attack of asthma.
G M Cochrane; J G Prior; C B Wolff
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  281     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1980 Sep 
Date Detail:
Created Date:  1981-01-29     Completed Date:  1981-01-29     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  705-7     Citation Subset:  AIM; IM    
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MeSH Terms
Anoxia / blood*
Asthma / blood*
Carbon Dioxide / blood*
Chronic Disease
Hydrogen-Ion Concentration
Oxygen / blood
Partial Pressure
Peak Expiratory Flow Rate
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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