| Chronic rhinosinusitis: Epidemiology and medical management. | |
| | |
MedLine Citation:
|
PMID: 21890184 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Chronic rhinosinusitis (CRS) affects 12.5% of the US population. On epidemiologic grounds, some association has been found between CRS prevalence and air pollution, active cigarette smoking, secondhand smoke exposure, perennial allergic rhinitis, and gastroesophageal reflux. The majority of pediatric and adult patients with CRS are immune competent. Data on genetic associations with CRS are still sparse. Current consensus definitions subclassify CRS into CRS without nasal polyposis (CRSsNP), CRS with nasal polyposis (CRSwNP), and allergic fungal rhinosinusitis (AFRS). Evaluation and medical management of CRS has been the subject of several recent consensus reports. The highest level of evidence for treatment for CRSsNP exists for saline lavage, intranasal steroids, and long-term macrolide antibiotics. The highest level of evidence for treatment of CRSwNP exists for intranasal steroids, systemic glucocorticoids, and topical steroid irrigations. Aspirin desensitization is beneficial for patients with aspirin-intolerant CRSwNP. Sinus surgery followed by use of systemic steroids is recommended for AFRS. Other modalities of treatment, such as antibiotics for patients with purulent infection and antifungal drugs for patients with AFRS, are potentially useful despite a lack of evidence from controlled treatment trials. The various modalities of medical treatment are reviewed in the context of recent consensus documents and the author's personal experience. |
| | |
Authors:
|
Daniel L Hamilos |
Related Documents
:
|
20088054 - The complexity of moving patients in today's maturing counterinsurgency environment: wh... 1765044 - Intramuscular injections through indwelling cannulae. 8254084 - The hierarchical factor structure of the wais-r for alcoholic adults. 3768094 - The impact on consumption of selling wine in grocery stores. 17456124 - Effect of reading additional safety information on planned use of over-the-counter anal... 2355754 - On studying the discourse of medical encounters. a critique of quantitative and qualita... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-9-2 |
Journal Detail:
|
Title: The Journal of allergy and clinical immunology Volume: - ISSN: 1097-6825 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-9-5 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 1275002 Medline TA: J Allergy Clin Immunol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved. |
Affiliation:
|
Massachusetts General Hospital, Division of Rheumatology, Allergy & Immunology, Boston, Mass. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Transurethral Resection of the Prostate with Monopolar Resectoscope: Single-surgeon Experience and L...
Next Document: In vitro maturation of canine oocytes co-cultured with bovine and canine granulosa cell monolayers.