Document Detail

Chronic recurrent multifocal osteomyelitis presenting as acute scoliosis: a case report and review of literature.
MedLine Citation:
PMID:  17912555     Owner:  NLM     Status:  MEDLINE    
Chronic relapsing multifocal osteomyelitis (CRMO) is a rare condition. It commonly affects the clavicle and pelvis. Rarely it can affect the spine. Spinal deformity due to CRMO is rare. We report a case of acute scoliosis due to CRMO. A 10-year-old girl with CRMO presented with acute painful scoliosis of her spine. She was neurologically intact. Imaging suggested a neoplastic process involving T10, L2 and L3. Further imaging and subsequent biopsy was performed and a diagnosis of CRMO was established. Spinal involvement with deformity is uncommon. It is commonly misdiagnosed as infection or a neoplasm and unnecessary aggressive surgical and antibiotic therapy instituted. A high index of suspicion is needed to diagnose this disease and thus manage it appropriately. This patient with a previously normal spine had a long right sided thoracic scoliosis. We think that the particular pattern of scoliosis was a protective mechanism to offload the right sided T10 vertebral pedicle. Prognosis is generally good although the disease can relapse and remit over many years. At 9 months follow up, the lesions were resolving and the deformity had resolved. CRMO presenting as acute scoliosis is rare and to our knowledge this is the second recognised case in the reported world literature.
Kedar Deogaonkar; Adel Ghandour; Alwyn Jones; Sashin Ahuja; Kathleen Lyons
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2007-10-03
Journal Detail:
Title:  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society     Volume:  17 Suppl 2     ISSN:  1432-0932     ISO Abbreviation:  Eur Spine J     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-28     Completed Date:  2009-01-16     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9301980     Medline TA:  Eur Spine J     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  S248-52     Citation Subset:  IM    
Trauma and Orthopaedics, University Hospital of Wales, Heath Park Avenue, Cardiff, CF14 4XW, UK.
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MeSH Terms
Acetaminophen / therapeutic use
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Back Pain / drug therapy,  etiology
Chronic Disease / therapy
Inflammation / drug therapy,  etiology
Lumbar Vertebrae / pathology,  physiopathology,  radiography
Magnetic Resonance Imaging
Osteomyelitis / complications*,  pathology*,  radiography
Scoliosis / etiology*,  pathology*,  radiography
Spine / pathology*,  physiopathology,  radiography
Thoracic Vertebrae / pathology,  physiopathology,  radiography
Tomography, X-Ray Computed
Treatment Outcome
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 103-90-2/Acetaminophen

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