Document Detail

Chronic persistent pulmonary embolism. Report of three cases.
MedLine Citation:
PMID:  7435515     Owner:  NLM     Status:  MEDLINE    
Nonresolution of acute pulmonary embolism and resultant chronic persistent pulmonary occlusion is uncommon; documentation of its occurrence in patients receiving anticoagulants is sparse. We report three cases with hemodynamic data and follow-up of up to seven years. All patients had mild to moderate dyspnea on exertion. All patients had normal resting pulmonary artery pressures; two patients demonstrated pulmonary hypertension with exercise. One patient underwent successful thromboendarterectomy but had subsequent reocclusion secondary to in situ thrombosis. With all patients receiving long-term anticoagulant therapy, there was no clinical recurrence of embolization or progression of symptoms. Patients with chronic persistent pulmonary embolism should be identified and should receive long-term follow-up. Therapy aimed at prevention of recurrent embolization is required. Pulmonary thromboendarterectomy is indicated for selected patients.
J W Shuck; J S Walder; T H Kam; H M Thomas
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of medicine     Volume:  69     ISSN:  0002-9343     ISO Abbreviation:  Am. J. Med.     Publication Date:  1980 Nov 
Date Detail:
Created Date:  1981-01-29     Completed Date:  1981-01-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  790-4     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Pressure
Chronic Disease
Follow-Up Studies
Heparin / administration & dosage
Injections, Intravenous
Injections, Subcutaneous
Middle Aged
Pulmonary Artery / physiopathology,  surgery
Pulmonary Embolism / therapy*
Time Factors
Vascular Resistance
Warfarin / administration & dosage
Reg. No./Substance:
81-81-2/Warfarin; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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