Document Detail

Chronic paroxysmal hemicrania and hemicrania continua responding to topiramate: two case reports.
MedLine Citation:
PMID:  17954009     Owner:  NLM     Status:  MEDLINE    
Chronic paroxysmal hemicrania (CPH) is a rare primary headache syndrome, which is classified along with cluster headache and short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing as a trigeminal autonomic cephalalgia (TACs). Hemicrania continua (HC) was previously classified as one of the TACs, but in the recent second classification of the International Headache Society this disorder was moved to the group of other primary headaches. Both CPH and HC are characterised by moderate to excruciating pain requiring pharmacological treatment; furthermore, both conditions are characterised by an absolute response to indomethacin, which represents one of the current diagnostic criteria for these two syndromes. Unfortunately, in about one-fourth of cases treatment with indomethacin may cause adverse events, mostly gastrointestinal. We report one subject with CPH and another with HC intolerant to indomethacin, who responded remarkably well to topiramate.
Cecilia Camarda; Rosolino Camarda; Roberto Monastero
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-10-22
Journal Detail:
Title:  Clinical neurology and neurosurgery     Volume:  110     ISSN:  0303-8467     ISO Abbreviation:  Clin Neurol Neurosurg     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-12-24     Completed Date:  2008-04-17     Revised Date:  2013-08-21    
Medline Journal Info:
Nlm Unique ID:  7502039     Medline TA:  Clin Neurol Neurosurg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  88-91     Citation Subset:  IM    
Adult Headache Centre, Department of Clinical Neuroscience, University of Palermo, Palermo, Italy.
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MeSH Terms
Fructose / analogs & derivatives*,  therapeutic use
Neuroprotective Agents / therapeutic use*
Trigeminal Autonomic Cephalalgias / classification,  drug therapy*
Reg. No./Substance:
0/Neuroprotective Agents; 0H73WJJ391/topiramate; 30237-26-4/Fructose

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