Document Detail


Chronic non-cancer-related pain : Long-term treatment with rapid-release and short-acting opioids in the context of misuse and dependency.
MedLine Citation:
PMID:  23340881     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Annually published data show a continual increase in the volume of opioid prescriptions in Germany, thus indicating an intensification of opioid therapy. The majority of opioids are prescribed to treat chronic non-cancer-related pain. On the basis of current guidelines, as well as in terms of the lack of data regarding long-term use of opioids and their effectiveness beyond a period of 3 months, this development must be viewed critically. With reference to four case reports, we discuss and evaluate opioid therapy in relation to medication misuse and the development of drug dependency. Particular emphasis is placed on the administration of rapid-release and short-acting opioid preparations, which we consider to be particularly problematic. A full-text English version of the article is available.The English full-text version of this article is available at SpringerLink (under"Supplemental").
Authors:
R Scharnagel; U Kaiser; A Schütze; R Heineck; G Gossrau; R Sabatowski
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-24
Journal Detail:
Title:  Schmerz (Berlin, Germany)     Volume:  -     ISSN:  1432-2129     ISO Abbreviation:  Schmerz     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8906258     Medline TA:  Schmerz     Country:  -    
Other Details:
Languages:  GER     Pagination:  -     Citation Subset:  -    
Affiliation:
UniversitätsSchmerzCentrum, Universitätsklinikum Carl Gustav Carus, Fetscherstr. 74, 01307, Dresden, Deutschland, ruediger.scharnagel@uniklinikum-dresden.de.
Vernacular Title:
Chronische nichttumorbedingte Schmerzen : Langzeitbehandlung mit schnell freisetzenden und kurz wirksamen Opioiden im Kontext von Missbrauch und Abhängigkeit.
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