Document Detail

Chronic myelomonocytic leukemia: an ultrastructural study by transmission and scanning electron microscopy.
MedLine Citation:
PMID:  265679     Owner:  NLM     Status:  MEDLINE    
The hematologic findings in three cases of chronic myelomonocytic leukemia are presented, with results of ultrastructural studies by transmission and scanning electron microscopy on two of the cases. In the peripheral blood there was a dual, non-lymphocytic, markedly increased population of granulocytes and monocytes. The granulocytes showed marked nuclear abnormality and nuclear cytoplasmic organelle asynchrony. In the marrow the majority of the cells appeared granulocytic but atypical forms and intermediate difficult to distinguish from monocyte precursors were evident by electron microscopy. The ultrastructural findings lend some support to the concept that the neoplastic granulocytes and monocytes having a common precursor.
L F Skinnider; R T Card; S Padmanabh
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  67     ISSN:  0002-9173     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  1977 Apr 
Date Detail:
Created Date:  1977-05-27     Completed Date:  1977-05-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  339-46     Citation Subset:  AIM; IM    
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MeSH Terms
Bone Marrow / ultrastructure
Bone Marrow Cells
Cell Transformation, Neoplastic
Leukemia, Myeloid / blood*,  diagnosis,  pathology
Microscopy, Electron, Scanning
Middle Aged
Thrombocytopenia / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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