Document Detail

Chronic myeloid leukemia with an unusual simple variant translocation: t(22;22)(q13;q11).
MedLine Citation:
PMID:  3933239     Owner:  NLM     Status:  MEDLINE    
A second example of chronic myeloid leukemia (CML) with the unusual simple variant t(22;22) is reported. In this case, break points are readily identified at bands q13 and q11. The nature of simple variant translocations in CML is discussed in the light of recent knowledge acquired from in situ hybridization of c-Ableson proto-oncogen DNA probes to metaphase spreads of CML patients.
M Gyger; C Perreault; R Belanger; Y Bonny
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta haematologica     Volume:  73     ISSN:  0001-5792     ISO Abbreviation:  Acta Haematol.     Publication Date:  1985  
Date Detail:
Created Date:  1985-12-12     Completed Date:  1985-12-12     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0141053     Medline TA:  Acta Haematol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  193-5     Citation Subset:  IM    
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MeSH Terms
Bone Marrow Cells
Chromosomes, Human, 21-22 and Y
Genetic Variation*
Leukemia, Myeloid / genetics*
Translocation, Genetic*

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