| Chronic myeloid leukemia in the Asia-Pacific region: current practice, challenges and opportunities in the targeted therapy era. | |
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MedLine Citation:
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PMID: 20430443 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chronic myeloid leukemia (CML) management varies across Asia due to disparities in affluence and healthcare provision. We surveyed CML management practice at 33 hospitals in 14 countries/regions to identify treatment challenges and opportunities for harmonization. Patients were generally treated according to international guidelines; however, tyrosine kinase inhibitors (TKIs) and molecular monitoring are inaccessible to many patients not covered by national insurance or eligible for subsidized treatment. Late diagnosis and suboptimal monitoring, often due to cost and accessibility issues, are challenges. Priorities for Asia include: extending accessibility to TKIs; specialist laboratory monitoring; and enriching data to support regional CML management guidelines. |
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Authors:
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Dong-Wook Kim; Shripad D Banavali; Udomsak Bunworasate; Yeow-Tee Goh; Peter Ganly; He Huang; Ian Irving; Saengsuree Jootar; Hyun-Gyung Goh; Liang-Piu Koh; Wei Li; Tomoki Naoe; Soo-Chin Ng; Visalachy Purushotaman; Harryanto Reksodiputro; Lee-Yung Shih; Jih-Luh Tang; Arinobu Tojo; Jianmin Wang; Raymond Wong |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Leukemia research Volume: 34 ISSN: 1873-5835 ISO Abbreviation: Leuk. Res. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-09-27 Completed Date: 2010-11-03 Revised Date: 2011-06-02 |
Medline Journal Info:
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Nlm Unique ID: 7706787 Medline TA: Leuk Res Country: England |
Other Details:
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Languages: eng Pagination: 1459-71 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Division of Hematology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea. dwkim@catholic.ac.kr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Asia Data Collection Delayed Diagnosis Drug Delivery Systems Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive / economics, therapy* Pacific Islands Patient Care Management / economics Protein Kinase Inhibitors / therapeutic use Protein-Tyrosine Kinases / antagonists & inhibitors |
| Chemical | |
Reg. No./Substance:
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0/Protein Kinase Inhibitors; EC 2.7.10.1/Protein-Tyrosine Kinases |
| Comments/Corrections | |
Comment In:
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Leuk Res. 2011 May;35(5):e53-4
[PMID:
21255835
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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