| Chronic myeloid leukemia from basics to bedside. | |
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MedLine Citation:
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PMID: 10557038 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The discovery of the Philadelphia chromosome and its consistent involvement in chronic myeloid leukemia (CML) was the first time that a relationship between a cytogenetic abnormality and malignancy was demonstrated. This review will try to provide an insight into the molecular mechanisms underlying this disease and outline the therapeutical options for patients with CML. |
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Authors:
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S Thijsen; G Schuurhuis; J van Oostveen; G Ossenkoppele |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Leukemia Volume: 13 ISSN: 0887-6924 ISO Abbreviation: Leukemia Publication Date: 1999 Nov |
Date Detail:
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Created Date: 1999-12-07 Completed Date: 1999-12-07 Revised Date: 2013-03-04 |
Medline Journal Info:
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Nlm Unique ID: 8704895 Medline TA: Leukemia Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1646-74 Citation Subset: IM |
Affiliation:
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Department of Hematology, Br 250, University Hospital Vrije Universiteit, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bone Marrow Purging Cell Transformation, Neoplastic / genetics Cytogenetic Analysis Fusion Proteins, bcr-abl / genetics, immunology Genes, abl / genetics Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics*, immunology, pathology, therapy* Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / genetics, immunology, pathology, therapy Philadelphia Chromosome* Signal Transduction / genetics |
| Chemical | |
Reg. No./Substance:
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0/Fusion Proteins, bcr-abl |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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