Document Detail

Chronic localized conjunctival chemosis.
MedLine Citation:
PMID:  8713933     Owner:  NLM     Status:  MEDLINE    
Conjunctival chemosis is a commonly encountered clinical finding stemming from the presence of excess fluid in the conjunctiva. It is typically self-limiting or reversible if the underlying condition is treated. The authors present a series of seven cases of chronic localized conjunctival chemosis. Each patient had a localized area of dependent conjunctival edema for >or= 6 months. Evaluation of each patient included clinical examination, laboratory studies, and neuroimaging to attempt to elucidate the pathogenesis of the chemosis. Conjunctival biopsy was performed in six of the seven patients. In all of the patients studied, clinical examination uncovered no definitive signs of local inflammation. Laboratory evaluation was normal, and neuroimaging failed to confirm obstruction of venous or lymphatic drainage. Conjunctival biopsies showed chronic tissue inflammation or lymphangiectasia. The diagnosis of chronic localized conjunctival chemosis (CLCC) can be made if localized conjunctival edema persists for 6 months. Evaluation of biopsy specimens supports the theory that CLCC may result from scarring and structural alteration of conjunctival lymphatics, which appears to irreversibly affect the distribution of fluid in the conjunctiva.
N S Kalin; S E Orlin; A E Wulc; K F Heffler; W C Frayer; M E Sulewski; R A Mittra; H D Cavanagh
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cornea     Volume:  15     ISSN:  0277-3740     ISO Abbreviation:  Cornea     Publication Date:  1996 May 
Date Detail:
Created Date:  1996-11-07     Completed Date:  1996-11-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8216186     Medline TA:  Cornea     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  295-300     Citation Subset:  IM    
Scheie Eye Institute, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.
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MeSH Terms
Body Fluids / metabolism
Chronic Disease
Conjunctiva / metabolism,  pathology
Conjunctival Diseases / metabolism*,  pathology
Edema / metabolism*,  pathology
Middle Aged
Time Factors

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