Document Detail

Chronic infusion of angiotensin II into the olfactory bulb elicits an increase in water intake.
MedLine Citation:
PMID:  6824944     Owner:  NLM     Status:  MEDLINE    
Chronic infusion of angiotensin II (ANG II) into the olfactory bulb (OB) elicited a moderate dipsogenesis which occurred only during the dark phase, essentially doubling the water-to-food intake ratio. Removal of the food from the ANG II-OB group reduced water consumption to the level of the saline-infused/food-deprived controls. These experiments suggest that ANG II may interact with the OB to alter the normal water/food relationship.
F M Chen; D P Healy; R Hawkins; M P Printz
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Brain research     Volume:  259     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-04-15     Completed Date:  1983-04-15     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  335-9     Citation Subset:  IM    
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MeSH Terms
Angiotensin II / pharmacology*
Drinking / drug effects*
Eating / drug effects
Injections, Intraventricular
Olfactory Bulb / drug effects*
Rats, Inbred Strains
Receptors, Angiotensin / drug effects
Water-Electrolyte Balance / drug effects
Grant Support
Reg. No./Substance:
0/Receptors, Angiotensin; 11128-99-7/Angiotensin II

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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