| Chronic inflammation increases risk in hemodialysis patients. | |
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MedLine Citation:
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PMID: 18711296 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chronic inflammation is the cause of malnutrition and cardiovascular disease in hemodialysis patients. The purpose of this study was to assess C Reactive Protein (CRP) as an inflammatory marker and to define the relationship between CRP and other inflammatory and nutritional factors in this group of patients. One hundred and fourteen hemodialysis patients undergoing chronic dialysis (3 times a week for at least 4 hours) in two hemodialysis centers were enrolled in this cross-sectional study. Anthropometric and laboratory data including CRP, Il-6, hemoglobin, serum ferritin, triglyceride, cholesterol, albumin, total protein and transferrin were measured. The Kt/V for adequacy of dialysis was also calculated. There was a statistically significant correlation between the mean CRP and albumin, hemoglobin, and transferrin; while such relation was not found with BMI, ferritin, the length of dialysis, triceps skin fold thickness, mid arm circumference, mid arm muscle circumference, and Kt/V. We conclude that the negative relationship between CRP and albumin, transferrin, and hemoglobin suggests a correlation between inflammatory and nutritional factors. |
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Authors:
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Effat Razeghi; Homeira Omati; Sima Maziar; Patricia Khashayar; Mitra Mahdavi-Mazdeh |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia Volume: 19 ISSN: 1319-2442 ISO Abbreviation: Saudi J Kidney Dis Transpl Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-19 Completed Date: 2008-12-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9436968 Medline TA: Saudi J Kidney Dis Transpl Country: Saudi Arabia |
Other Details:
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Languages: eng Pagination: 785-9 Citation Subset: IM |
Affiliation:
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Department of Nephrology, Sina Hospital, Tehran, Iran. razegia@sina.tums.ac.ir |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Biological Markers / analysis, blood Blood Proteins / metabolism C-Reactive Protein / analysis Cardiovascular Diseases / etiology Cholesterol / blood Cross-Sectional Studies Ferritins / blood Humans Inflammation / complications* Interleukin-6 / blood Malnutrition / etiology Middle Aged Renal Dialysis / adverse effects* Risk Factors Transferrin / metabolism Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Blood Proteins; 0/Interleukin-6; 0/Triglycerides; 11096-37-0/Transferrin; 57-88-5/Cholesterol; 9007-41-4/C-Reactive Protein; 9007-73-2/Ferritins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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