Document Detail


Chronic inflammation increases risk in hemodialysis patients.
MedLine Citation:
PMID:  18711296     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chronic inflammation is the cause of malnutrition and cardiovascular disease in hemodialysis patients. The purpose of this study was to assess C Reactive Protein (CRP) as an inflammatory marker and to define the relationship between CRP and other inflammatory and nutritional factors in this group of patients. One hundred and fourteen hemodialysis patients undergoing chronic dialysis (3 times a week for at least 4 hours) in two hemodialysis centers were enrolled in this cross-sectional study. Anthropometric and laboratory data including CRP, Il-6, hemoglobin, serum ferritin, triglyceride, cholesterol, albumin, total protein and transferrin were measured. The Kt/V for adequacy of dialysis was also calculated. There was a statistically significant correlation between the mean CRP and albumin, hemoglobin, and transferrin; while such relation was not found with BMI, ferritin, the length of dialysis, triceps skin fold thickness, mid arm circumference, mid arm muscle circumference, and Kt/V. We conclude that the negative relationship between CRP and albumin, transferrin, and hemoglobin suggests a correlation between inflammatory and nutritional factors.
Authors:
Effat Razeghi; Homeira Omati; Sima Maziar; Patricia Khashayar; Mitra Mahdavi-Mazdeh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia     Volume:  19     ISSN:  1319-2442     ISO Abbreviation:  Saudi J Kidney Dis Transpl     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-19     Completed Date:  2008-12-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9436968     Medline TA:  Saudi J Kidney Dis Transpl     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  785-9     Citation Subset:  IM    
Affiliation:
Department of Nephrology, Sina Hospital, Tehran, Iran. razegia@sina.tums.ac.ir
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MeSH Terms
Descriptor/Qualifier:
Aged
Biological Markers / analysis,  blood
Blood Proteins / metabolism
C-Reactive Protein / analysis
Cardiovascular Diseases / etiology
Cholesterol / blood
Cross-Sectional Studies
Ferritins / blood
Humans
Inflammation / complications*
Interleukin-6 / blood
Malnutrition / etiology
Middle Aged
Renal Dialysis / adverse effects*
Risk Factors
Transferrin / metabolism
Triglycerides / blood
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Blood Proteins; 0/Interleukin-6; 0/Triglycerides; 11096-37-0/Transferrin; 57-88-5/Cholesterol; 9007-41-4/C-Reactive Protein; 9007-73-2/Ferritins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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