Document Detail

Chronic idiophatic urticaria and Helicobacter pylori: a specific pattern of gastritis and urticaria remission after Helicobacter pylori eradication.
MedLine Citation:
PMID:  23058028     Owner:  NLM     Status:  Publisher    
Chronic urticaria (CU) is defined as the occurrence of spontaneous wheals for a duration of more than 6 weeks and is the most frequent skin disease, with prevalence ranging between 15 and 25 percent, and is a seriously disabling condition, with social isolation and mood changes causing a significant degree of dysfunction and quality of life impairment to many patients. The main clinical features of CU are the repeated occurrence of transient eruptions of pruritic wheals or patchy erythema on the skin that last less than 24 hours and disappear without sequelae. CU is often defined as Chronic idiopathic urticaria (CIU) because the causes of CU remain unknown in the great majority (70-95 percent) of patients. Drugs, food, viruses, alimentary conservative substances or inhalant substances often seem to be involved in determining CIU skin flare. Despite a general agreement that bacteria infections and parasitic infestations can be involved in the pathogenesis of CIU, proven evidence of these relationships is lacking. The aim of the present study is to evaluate the prevalence of Helicobacter pylori (Hp) infection, and the extension and severity of gastritis in a group of CIU patients compared to controls and to evaluate the effectiveness of eradication of Hp on the CIU symptomatology, and the role of Hp infection in pathogenesis of CIU.
S Persechino; B Annibale; C Caperchi; F Persechino; A Narcisi; A Tammaro; M Milione; V Corleto
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Publication Detail:
Journal Detail:
Title:  International journal of immunopathology and pharmacology     Volume:  25     ISSN:  0394-6320     ISO Abbreviation:  Int J Immunopathol Pharmacol     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-10-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8911335     Medline TA:  Int J Immunopathol Pharmacol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  765-770     Citation Subset:  -    
U.O.C. Dermatology, Sant’Andrea Hospital, Faculty of Psychology and Medicine of Rome Sapienza University of Rome, Italy.
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