| Chronic hypovolemia associated with accelerated hypertension and orthostatic hypotension in a patient on continuous ambulatory peritoneal dialysis. | |
| | |
MedLine Citation:
|
PMID: 1292347 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We report a patient with nondiabetic end-stage renal disease on continuous ambulatory peritoneal dialysis (CAPD) associated with chronic hypovolemia. Despite the administration of nilvadipine, the patient showed accelerated hypertension and concomitantly orthostatic hypotension. Plasma renin activity was markedly high, and blockade of angiotensin II action by captopril or an angiotension II antagonist decreased the supine blood pressure. This indicated that the enhanced activity of the renin-angiotensin system was the principal cause of the supine hypertension. The plasma concentration of norepinephrine was also very high. After correction of hypovolemia by blood transfusion, the enhancement of the renin-angiotensin system and high plasma norepinephrine level were reduced, and symptomatic orthostatic hypotension disappeared. The accelerated hypertension was easily controlled by the administration of low-dose captopril and nilvadipine. These findings suggest that chronic hypovolemia related to the intractable supine hypertension as well as orthostatic hypotension. Hypovolemia-induced enhancement of the renin-angiotensin system and sympathetic nerve activity may cause vasoconstrictive hypertension in patients on CAPD. |
| | |
Authors:
|
T Touma; H Muratani; K Iseki; N Kawazoe; S Takishita; K Fukiyama |
Related Documents
:
|
6342907 - Surgical reversal of renovascular hypertension in rats: changes in blood pressure, plas... 870227 - The effect of high sodium intake and angiotensin antagonist in rabbits with severe and ... 6400117 - Humoral changes during and following coronary bypass surgery: relationship to postopera... 514427 - Effect of indomethacin on renal function and plasma renin activity in dogs with chronic... 8800127 - Transesophageal echocardiographic assessment of the contribution of intrinsic tissue th... 20227347 - Effects of beta blockers and calcium-channel blockers on within-individual variability ... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: American journal of nephrology Volume: 12 ISSN: 0250-8095 ISO Abbreviation: Am. J. Nephrol. Publication Date: 1992 |
Date Detail:
|
Created Date: 1993-03-29 Completed Date: 1993-03-29 Revised Date: 2007-02-14 |
Medline Journal Info:
|
Nlm Unique ID: 8109361 Medline TA: Am J Nephrol Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 461-5 Citation Subset: IM |
Affiliation:
|
Third Department of Internal Medicine, School of Medicine, University of The Ryukyus, Okinawa, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Blood Volume* Humans Hypertension, Renal / complications*, physiopathology Hypotension, Orthostatic / complications* Kidney Failure, Chronic / complications, physiopathology, therapy Male Middle Aged Peritoneal Dialysis, Continuous Ambulatory* Renin-Angiotensin System / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Disappearance of immune deposits with EDTA chelation therapy in a case of IgA nephropathy.
Next Document: Membranoproliferative glomerulonephritis associated with multicentric angiofollicular lymph node hyp...