Document Detail

Chronic histopathological effects of parathion and 2,4-D on female gonads of Chasmagnathus granulata (Decapoda, Brachyura).
MedLine Citation:
PMID:  7927078     Owner:  NLM     Status:  MEDLINE    
Female crabs of Chasmagnathus granulata, sampled at the external zone of the Rio de la Plata estuary, were chronically exposed to the pesticides parathion and 2,4-D, both of which have been extensively applied to crops in Argentina for a decade and have been detected several times above permissible levels in the estuary. After 2 months of female exposure to the pesticides during the reproductive season, the crabs' ovaries were dissected and fixed in Bouin's solution, to assess the possible effects of pesticides at the histological level. Parathion caused a significant increase in both previtellogenic and vitellogenic oocyte size, as well as a loss of the normal spherical shape of the oocytes. With 2,4-D, a significant decrease in vitellogenic oocyte size was noted, whereas the number of atretic follicles increased as a result of exposure to this herbicide. Several hypothetical mechanisms of action of these pesticides are discussed in relation to the effects observed. Although assayed concentrations were relatively high with respect to mean values detected in the mentioned estuary and its influents, persistent peaks may occur, especially in sediments. This work suggests a high potential risk from the pesticides studied to the reproductive performance of local aquatic fauna.
E M Rodríguez; M Schuldt; L Romano
Related Documents :
17016028 - Simultaneous analysis of 10 pyrethroid pesticides in natural medicines by gc/ms with ne...
10344078 - Determination of acrinathrin residues in honey and beeswax.
12052638 - Food contamination by metals and pesticides in the european union. should we worry?
15543728 - Annual variations of pesticide concentrations in great lakes precipitation.
22173458 - Reconciling the omnivory-stability debate.
14681838 - Effects of food restriction on peroxisome proliferator-activated receptor-gamma and glu...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association     Volume:  32     ISSN:  0278-6915     ISO Abbreviation:  Food Chem. Toxicol.     Publication Date:  1994 Sep 
Date Detail:
Created Date:  1994-10-25     Completed Date:  1994-10-25     Revised Date:  2006-03-13    
Medline Journal Info:
Nlm Unique ID:  8207483     Medline TA:  Food Chem Toxicol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  811-8     Citation Subset:  IM    
Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, INEUCI (CONICET), Ciudad Universitaria (Pab. II), Argentina.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
2,4-Dichlorophenoxyacetic Acid / toxicity*
Brachyura / drug effects*
Oocytes / drug effects,  pathology
Parathion / toxicity*
Water Pollutants, Chemical / toxicity*
Reg. No./Substance:
0/Water Pollutants, Chemical; 56-38-2/Parathion; 94-75-7/2,4-Dichlorophenoxyacetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Binding properties of lactic acid bacteria from 'Idly' towards food-borne mutagens.
Next Document:  Use of precision-cut liver slices for studies of unscheduled DNA synthesis.