Document Detail


Chronic hepatitis ameliorates anaemia in haemodialysis patients.
MedLine Citation:
PMID:  18331433     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Study for influence of chronic hepatitis (CH) on anaemia in haemodialysis (HD) patients remains inconclusive. We aim to characterize the red cell status between CH and hepatitis-free groups among the HD population. METHODS: We retrospectively analysed 80 chronic HD patients from Taipei Medical University Hospital with monthly sampled biochemical study between December 2004 and December 2005. Data classified according to the hepatitis-free, chronic hepatitis B and C groups were expressed as mean +/- standard deviation. Student's t-test and anova were used to determine the mean difference for continuous variables. RESULTS: Age, Kt/V, systolic or diastolic blood pressure, body mass index, total cholesterol and triglyceride were not different between CH and hepatitis-free groups. HD duration (P = 0.0002), aspartate (P < 0.0001), alanine aminotransferase (P < 0.0001), alkaline phosphatase (P = 0.04), haemoglobin (P = 0.0066) and haematocrit (P = 0.002) were significantly more elevated in the CH group demanding less erythropoietin dose than in the hepatitis-free group. CONCLUSION: Our study demonstrated that lessened anaemia was observed in CH, which demanded less erythropoietin dose.
Authors:
Yi-Lung Lin; Chi-Wei Lin; Chieh-Hua Lee; I-Chun Lai; His-Hsien Chen; Tzen-Wen Chen
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Publication Detail:
Type:  Journal Article     Date:  2008-03-05
Journal Detail:
Title:  Nephrology (Carlton, Vic.)     Volume:  13     ISSN:  1440-1797     ISO Abbreviation:  Nephrology (Carlton)     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-05-14     Completed Date:  2008-06-26     Revised Date:  2009-04-16    
Medline Journal Info:
Nlm Unique ID:  9615568     Medline TA:  Nephrology (Carlton)     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  289-93     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Division of Nephrology, Taipei Medical University and Hospital, Taipei, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Alanine Transaminase / blood
Anemia / blood,  drug therapy*,  etiology,  virology
Aspartate Aminotransferases / blood
Erythropoietin, Recombinant / administration & dosage*
Female
Hematinics / administration & dosage*
Hematocrit
Hemoglobins / metabolism
Hepatitis B, Chronic / blood,  complications*
Hepatitis C, Chronic / blood,  complications*
Humans
Injections, Intravenous
Kidney Diseases / blood,  complications,  therapy*
Male
Middle Aged
Renal Dialysis*
Retrospective Studies
Chemical
Reg. No./Substance:
0/Erythropoietin, Recombinant; 0/Hematinics; 0/Hemoglobins; EC 2.6.1.1/Aspartate Aminotransferases; EC 2.6.1.2/Alanine Transaminase
Comments/Corrections
Comment In:
Nephrology (Carlton). 2009 Feb;14(1):137   [PMID:  19335848 ]

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