| Chronic granulomatous disease presenting with hypogammaglobulinemia. | |
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MedLine Citation:
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PMID: 21721378 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder caused by inherited defects in the nicotinamide adenine dinucleotide phosphate oxidase complex. The neutrophils of patient with CGD can ingest bacteria normally, but the oxidative processes that lead to superoxide anion formation, hydrogen peroxide production, nonoxidative pathway activation, and bacterial killing are impaired. Serious infections result from microorganisms that produce catalase. Immunoglobulin levels of patients with CGD are usually normal or elevated. We describe a patient with CGD associated with hypogammaglobulinemia, an unusual co-occurrence. |
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Authors:
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D Hanoglu; T T Ozgür; D Ayvaz; M Y Köker; O Sanal |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunología Volume: 21 ISSN: 1018-9068 ISO Abbreviation: J Investig Allergol Clin Immunol Publication Date: 2011 |
Date Detail:
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Created Date: 2011-07-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9107858 Medline TA: J Investig Allergol Clin Immunol Country: Spain |
Other Details:
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Languages: eng Pagination: 310-2 Citation Subset: IM |
Affiliation:
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Hacettepe University Faculty of Medicine, Ankara, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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