Document Detail


Chronic granulocytic leukemia.
MedLine Citation:
PMID:  6205231     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article reviews the definition, etiology, epidemiology, cytogenetics, and diagnosis of chronic granulocytic leukemia (CGL). There is detailed consideration of clinical and laboratory findings, the natural history of CGL, and the selection of therapy at different stages of the disease. The roles of bone marrow transplantation and of newer experimental therapeutic approaches are discussed.
Authors:
A S Spiers
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  The Medical clinics of North America     Volume:  68     ISSN:  0025-7125     ISO Abbreviation:  Med. Clin. North Am.     Publication Date:  1984 May 
Date Detail:
Created Date:  1984-09-06     Completed Date:  1984-09-06     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  2985236R     Medline TA:  Med Clin North Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  713-27     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Asparaginase / administration & dosage
Bone Marrow Transplantation
Busulfan / therapeutic use
Chromosomes, Human, 21-22 and Y
Cyclophosphamide / administration & dosage
Cytarabine / administration & dosage
Daunorubicin / administration & dosage
Female
Humans
Hydroxyurea / therapeutic use
Leukapheresis
Leukemia, Myeloid / diagnosis*,  epidemiology,  etiology,  genetics,  therapy
Male
Methotrexate / administration & dosage
Middle Aged
Palliative Care
Prednisolone / administration & dosage
Prednisone / administration & dosage
Thioguanine / administration & dosage
Vincristine / administration & dosage
Grant Support
ID/Acronym/Agency:
CA157078/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
0/TRAMPCOL protocol; 127-07-1/Hydroxyurea; 147-94-4/Cytarabine; 154-42-7/Thioguanine; 20830-81-3/Daunorubicin; 50-18-0/Cyclophosphamide; 50-24-8/Prednisolone; 53-03-2/Prednisone; 55-98-1/Busulfan; 57-22-7/Vincristine; 59-05-2/Methotrexate; EC 3.5.1.1/Asparaginase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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