Document Detail

Chronic frequent premature ventricular complexes originating from right and non-right ventricular outflow tracts.
MedLine Citation:
PMID:  21173513     Owner:  NLM     Status:  In-Data-Review    
Frequent premature ventricular complexes (PVCs) from the right ventricular outflow tract (RVOT) have recently been reported to be a cause of dilated cardiomyopathy. We studied the clinical impact of the elimination of PVCs from RVOT and non-RVOT.Thirty-six patients with symptomatic PVCs that were treated with radiofrequency catheter ablation (RFCA) were studied. The patients were assigned to one of two groups according to the origin of the PVCs (group I, RVOT-origin, n = 24; group II, non-RVOT-origin, n = 12) and observed for 10.5 ± 7.1 months.The burden of PVCs at baseline was 19.7 ± 10.6% and 18.7 ± 8.7% in group I and group II, respectively (P = 0.779). In group II, hypertension was more common (16.7% versus 58.3%, P = 0.020) and LV diastolic function was worse (Em, 8.7 ± 3.0 versus 6.4 ± 1.8 cm/second, P = 0.018). The LV end diastolic volume index (LVEDVI) decreased in both groups (59.7 ± 14.6 to 50.9 ± 9.6 mL/m(2), P = 0.004 in group I; 60.0 ± 19.9 to 51.6 ± 12.4 mL/m(2), P = 0.044 in group II), while the left atrial volume index (LAVI) decreased only in group I (36.7 ± 11.7 to 31.7 ± 10.0 mL/m(2), P = 0.002 in group I; 35.6 ± 11.9 to 33.8 ± 10.3 mL/m(2), P = 0.317 in group II). The left ventricular ejection fraction (LVEF) significantly improved in both groups (51.1 ± 6.6 to 59.8 ± 7.2 %, P < 0.01 in group I; 49.9 ± 6.9 to 59.0 ± 5.9 %, P < 0.01 in group II).RFCA of PVCs leads to a reduction of LV volume and improvement of LV systolic function regardless of the origin of the PVCs. Conversely, a non-RVOT-origin as well as an RVOT-origin of the PVCs can cause DCM-like changes in the left ventricle.
Yong-Hyun Kim; Seong-Mi Park; Hong Euy Lim; Hui-Nam Pak; Young-Hoon Kim; Wan-Joo Shim
Related Documents :
3079203 - Potassium and magnesium status in ischaemic heart disease.
4036983 - Adverse effects due to morphine sulfate. challenge to previous clinical doctrine.
17125503 - Children undergoing cardiac surgery for complex cardiac defects show imbalance between ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International heart journal     Volume:  51     ISSN:  1349-3299     ISO Abbreviation:  Int Heart J     Publication Date:  2010  
Date Detail:
Created Date:  2010-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101244240     Medline TA:  Int Heart J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  388-93     Citation Subset:  IM    
Division of Cardiology, Department of Medicine, Korea University Anam Hospital.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Angioscopic study of silent plaque disruption in nonischemic related coronary artery in patients wit...
Next Document:  Detection of diastolic potentials around the mitral annulus of structurally normal human hearts.