Document Detail

Chronic food restriction and the circadian rhythms of pituitary-adrenal hormones, growth hormone and thyroid-stimulating hormone.
MedLine Citation:
PMID:  3035995     Owner:  NLM     Status:  MEDLINE    
Adult male Sprague-Dawley rats were subjected to food restriction so that they ate 65% of food ingested by control rats. While control rats had free access to food over the 24-hour period, food-restricted rats were provided with food daily at 10 a.m. The experimental period lasted for 34 days. On day 35, rats from both experimental groups were killed at 08.00, 11.00, 14.00, 24.00 and 02.00 h. Food restriction modified the circadian rhythms of ACTH and corticosterone. In addition, total circulating corticosterone throughout the day was higher in food-restricted than in control rats. In contrast, food restriction resulted in depressed secretion of thyroid-stimulating hormone and growth hormone. The results indicate that time of food availability entrained circadian corticosterone rhythm but not thyroid-stimulating hormone and growth hormone rhythms.
A Armario; J L Montero; T Jolin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of nutrition & metabolism     Volume:  31     ISSN:  0250-6807     ISO Abbreviation:  Ann. Nutr. Metab.     Publication Date:  1987  
Date Detail:
Created Date:  1987-07-02     Completed Date:  1987-07-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8105511     Medline TA:  Ann Nutr Metab     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  81-7     Citation Subset:  IM    
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MeSH Terms
Adrenal Glands / anatomy & histology
Adrenocorticotropic Hormone / blood*
Body Weight
Circadian Rhythm*
Corticosterone / blood*
Growth Hormone / blood*
Organ Size
Pituitary Gland / anatomy & histology
Rats, Inbred Strains
Thyrotropin / blood*
Reg. No./Substance:
50-22-6/Corticosterone; 9002-60-2/Adrenocorticotropic Hormone; 9002-71-5/Thyrotropin; 9002-72-6/Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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