Document Detail


Chronic fatigue syndrome. A brief review of functional disturbances and potential therapy.
MedLine Citation:
PMID:  16230991     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The chronic fatigue syndrome (CFS) is debilitating for both athletes and the general population. A review of etiology and mechanisms underlying functional disturbances is undertaken to provide a valid basis for therapeutic options. The review focuses on CFS as characterized by standard diagnostic criteria, building on previous reviews through use of articles identified by Medline search. Overtraining, a negative energy balance, excessive physical or environmental stress, disorders of personality and affect, dysfunction of the hypophyseal-pituitary adrenal axis, hormonal imbalance, nutritional deficits, immune suppression or activation and chronic infection have all been proposed as factors precipitating CFS, but none of these precipitants are observed consistently. Impairments of peak aerobic power and muscle strength, together with many functional disturbances, seem related to patient- or physician-imposed inactivity. Once CFS is established, treatment should aim at breaking the vicious cycle of effort avoidance, deterioration in physical condition and increasing fatigue through a combination of psychotherapy, general encouragement and a progressive exercise regimen.
Authors:
R J Shephard
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of sports medicine and physical fitness     Volume:  45     ISSN:  0022-4707     ISO Abbreviation:  J Sports Med Phys Fitness     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-10-18     Completed Date:  2006-02-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376337     Medline TA:  J Sports Med Phys Fitness     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  381-92     Citation Subset:  IM    
Affiliation:
Faculty of Physical Education and Health and , Department of Public Health Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada. royjshep@mountain-inter.net
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MeSH Terms
Descriptor/Qualifier:
Autoimmunity
Cognitive Therapy
Exercise / physiology
Exercise Therapy
Fatigue Syndrome, Chronic / diagnosis*,  etiology,  therapy
Humans
Nutritional Status / physiology
Physical Education and Training
Sports / physiology*,  psychology
Sports Medicine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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