Document Detail

Chronic erosive gastritis: clinical, diagnostic, and pathological features in nine patients.
MedLine Citation:
PMID:  7102635     Owner:  NLM     Status:  MEDLINE    
We have recognized nine patients with gastric mucosal lesions which were characterized by an erosion with surrounding mucosal elevation. This lesions has previously been called chronic erosive or varioliform gastritis. Patients were investigated because of upper gastrointestinal symptoms (n = 7), weight loss (n = 2), and/or bleeding (n = 3). Radiologically the appearance was of typical target lesions. Pathological features included pseudopyloric metaplasia, pyloric gland hyperplasia, acute and chronic inflammation, edema, and fibrosis. Atypia was present in biopsies from four patients and in one was incorrectly interpreted as representing intramucosal carcinoma. The remaining patients were treated with antacids and/or cimetidine with resolution of symptoms and in five patients repeat endoscopy demonstrated resolution of the lesions. Chronic erosive gastritis may cause upper gastrointestinal symptoms indistinguishable from peptic ulceration. Greater numbers of patients will have to be treated in a controlled fashion to determine the natural history of the disease and the most efficacious treatment.
P H Green; R P Gold; C C Marboe; L M Weinberg; J P Goldfarb; T A Brasitus
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  77     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1982 Aug 
Date Detail:
Created Date:  1982-09-17     Completed Date:  1982-09-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  543-7     Citation Subset:  IM    
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MeSH Terms
Chronic Disease
Diagnosis, Differential
Gastritis / diagnosis*,  pathology,  radiography
Peptic Ulcer / diagnosis
Stomach / pathology,  radiography
Stomach Neoplasms / diagnosis

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