| Chronic effect of ferulic acid from Pseudosasa japonica leaves on enhancing exercise activity in mice. | |
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MedLine Citation:
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PMID: 20878702 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ferulic acid derived from Pseudosasa japonica leaves, which possessed antioxidative potentials with DPPH- (54%) and ABTs- (65%) radical scavenging activities, and lipid-peroxidation inhibitory activity (71%), was orally administered to mice for 12 days in order to investigate its effects on exercise endurance capacity and alterations of antioxidant defense systems. Exhaustive swimming time was increased in the ferulic acid-supplemented group compared with the control group on days 6 and 12 (1.7- and 1.8-fold, respectively). When the mice were exhaustively exercised for 2 consecutive days, a high decrease (53%) was shown in the control group, but no change was found in the ferulic acid-treated group. The administration of ferulic acid significantly protected the depletion of enzymatic- and non enzymatic-antioxidants due to exhaustive exercise. Also, lipid-peroxidation levels decreased in the ferulic acid-treated group compared with the non exercised- and control-groups. These results suggest that ferulic acid from Pseudosasa japonica leaves has a chronic effect on endurance exercise capacity, which is attributed to its ability to ameliorate oxidative stress by improving antioxidant potentials. |
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Authors:
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Yanghee You; Kyungmi Kim; Ho-Geun Yoon; Kwang-Won Lee; Jeongmin Lee; Jiyeon Chun; Dong-Hoon Shin; Jeongjin Park; Woojin Jun |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Phytotherapy research : PTR Volume: 24 ISSN: 1099-1573 ISO Abbreviation: Phytother Res Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-29 Completed Date: 2011-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8904486 Medline TA: Phytother Res Country: England |
Other Details:
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Languages: eng Pagination: 1508-13 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 John Wiley & Sons, Ltd. |
Affiliation:
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Department of Food and Nutrition, Chonnam National University, Gwangju 550-757, Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antioxidants / pharmacology Coumaric Acids / pharmacology* Free Radical Scavengers / pharmacology Lipid Peroxidation Male Mice Mice, Inbred ICR Motor Activity / drug effects* Physical Endurance / drug effects* Plant Leaves / chemistry Poaceae / chemistry* Swimming |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Coumaric Acids; 0/Free Radical Scavengers; 1135-24-6/ferulic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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