Document Detail

Chronic cutaneous candidiasis in bottle-nosed dolphins.
MedLine Citation:
PMID:  924876     Owner:  NLM     Status:  MEDLINE    
In a 20-month period, generalized chronic cutaneous candidiasis developed in 3 performing bottle-nosed dolphins kept in an indoor pool. Extensive esophagogastric ulcerations were observed in 2 of the dolphins, each of which died, presumably because of these lesions. The 3rd dolphin died during a surgical procedure and did not have any esophagogastric ulcerations. Candida albicans was the only organism isolated from skin lesions but was not isolated from adjacent normal skin of dolphins. Treatment with antifungal drugs was unsuccessful. Subsequently, immunopotentiating treatment with levamisole phosphate resulted in formation of granulation tissue and healing of the skin lesions.
S Nakeeb; S P Targowski; S Spotte
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  171     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  1977 Nov 
Date Detail:
Created Date:  1978-01-27     Completed Date:  1978-01-27     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  961-5     Citation Subset:  IM    
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MeSH Terms
Animals, Zoo*
Candidiasis, Cutaneous / drug therapy,  pathology,  veterinary*
Esophageal Diseases / pathology,  veterinary
Esophagus / pathology
Levamisole / therapeutic use
Nystatin / therapeutic use
Skin / pathology
Stomach / pathology
Stomach Ulcer / pathology,  veterinary
Ulcer / pathology,  veterinary
Reg. No./Substance:
1400-61-9/Nystatin; 14769-73-4/Levamisole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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