Document Detail

Chronic cough.
MedLine Citation:
PMID:  18685405     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: Chronic cough is common and distressing, especially against the background of life-threatening illness. It is a symptom that has received scant attention, often eclipsed by pain, breathlessness, nausea and vomiting. RECENT FINDINGS: This paper reviews the recent literature in cough research: its mechanism, assessment and management. There is so little research from supportive and palliative care that much of our knowledge is extrapolated from research elsewhere. Objective measurement of cough has been facilitated by advances in measuring devices, while subjective assessment tools including cough-specific quality of life questionnaires are now available. These are practical, simple to use and can be incorporated into daily practice. A few drugs have come in and out of favour but there has been no solid advance in therapeutic options in over a decade. SUMMARY: The availability of simple assessment tools places the imperative on clinicians to be more systematic in assessment of cough and its interventions. The mainstay of oral therapy for symptom control remains dextromethorphan, codeine and morphine. The potential for research is huge: from basic scientific understanding to clinical trials of innovative therapies.
Bee Wee
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in supportive and palliative care     Volume:  2     ISSN:  1751-4266     ISO Abbreviation:  -     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-08-07     Completed Date:  2008-11-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101297402     Medline TA:  Curr Opin Support Palliat Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  105-9     Citation Subset:  IM    
Sir Michael Sobell House, Oxford Radcliffe Hospitals NHS Trust and Nuffield Department of Medicine, Medical Sciences Division and Harris Manchester College, Oxford University, Oxford, UK.
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MeSH Terms
Analgesics, Opioid / therapeutic use
Antitussive Agents / therapeutic use*
Chronic Disease
Codeine / therapeutic use
Cough / drug therapy*,  physiopathology,  psychology
Dextromethorphan / therapeutic use
Morphine / therapeutic use
Palliative Care
Reg. No./Substance:
0/Analgesics, Opioid; 0/Antitussive Agents; 125-71-3/Dextromethorphan; 57-27-2/Morphine; 76-57-3/Codeine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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