Document Detail

Chronic changes in the walls of experimentally produced aneurysms in sheep.
MedLine Citation:
PMID:  451826     Owner:  NLM     Status:  MEDLINE    
Twenty-seven saccular aneurysms were fashioned on the common carotid arteries of sheep using the venous transplants with a side-to-side anastomosis. The vessels were examined at varying intervals up to eight months postoperatively. The venous sacs exhibited severe phlebosclerosis of rapid progression and gross loss of muscle, and elastica was most prominent at the fundus. Some aneurysms leaked, some contained mural thrombus and several exhibited minimal quantities of lipid. The histologic changes were similar to those in man and experimental models entailing severe hemodynamic stress and can be regarded as atherosclerotic in nature.
W E Stehbens
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery, gynecology & obstetrics     Volume:  149     ISSN:  0039-6087     ISO Abbreviation:  Surg Gynecol Obstet     Publication Date:  1979 Jul 
Date Detail:
Created Date:  1979-08-29     Completed Date:  1979-08-29     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0101370     Medline TA:  Surg Gynecol Obstet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  43-8     Citation Subset:  AIM; IM    
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MeSH Terms
Arteriovenous Fistula / etiology,  pathology*
Carotid Arteries / pathology*,  surgery
Carotid Artery Diseases / pathology*
Jugular Veins / pathology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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