Document Detail

Chronic arthritis in two children with partial deletion of chromosome 18.
MedLine Citation:
PMID:  3625639     Owner:  NLM     Status:  MEDLINE    
We describe 2 children with a partial deletion of chromosome 18 and chronic arthritis. A boy with r(18)(p11.3; q23) lacked serum IgA and had arthritis affecting both knees. A girl with del (18)(q21.2; q22) had arthritis in 5 joints. Her serum IgA was normal. In both children, the arthritis responded to nonsteroidal antiinflammatory drugs.
R E Petty; P Malleson; D K Kalousek
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  14     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  1987 Jun 
Date Detail:
Created Date:  1987-10-13     Completed Date:  1987-10-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  586-7     Citation Subset:  IM    
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MeSH Terms
Arthritis / genetics*
Child, Preschool
Chromosome Aberrations*
Chromosome Deletion*
Chromosomes, Human, Pair 18*
Chronic Disease
Dysgammaglobulinemia / genetics
IgA Deficiency
Ring Chromosomes*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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