Document Detail

Chronic angina pectoris: inadequacies of current therapy.
MedLine Citation:
PMID:  15365289     Owner:  NLM     Status:  MEDLINE    
Chronic angina is a major medical problem in the United States with more than 6 million patients affected, a number that will increase substantially because of the progressive aging of the population. The annual mortality rate for patients with chronic angina is approximately 2%, but is much higher in certain subsets of patients, particularly the elderly. Angina is also associated with major social and economic burdens. Because of poor symptom control and hemodynamic, as well as other drug side effects, angina is commonly associated with a poor quality of life. No new class of drug has been available for angina treatment in more than two decades, and current medications frequently fail to provide adequate symptom control. Thus, the majority of patients are taking two or three antianginal medications. New agents that modulate myocardial metabolism have shown antianginal efficacy, a favorable side-effect profile, and an absence of hemodynamic effects.
John O Parker
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of geriatric cardiology     Volume:  13     ISSN:  1076-7460     ISO Abbreviation:  Am J Geriatr Cardiol     Publication Date:    2004 Sep-Oct
Date Detail:
Created Date:  2004-09-14     Completed Date:  2006-08-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9215283     Medline TA:  Am J Geriatr Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  261-6     Citation Subset:  IM    
Copyright Information:
Copyright 2004 Le Jacq Communications, Inc.
Division of Cardiology, Kingston General Hospital, Kingston, Ontario, Canada K7L 2V7.
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MeSH Terms
Angina Pectoris / economics,  surgery,  therapy*
Angioplasty, Transluminal, Percutaneous Coronary
Chronic Disease
Coronary Artery Bypass
Cost of Illness
Quality of Life
United States / epidemiology
Comment In:
Am J Geriatr Cardiol. 2004 Sep-Oct;13(5):237-8   [PMID:  15365285 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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