Document Detail

Chronic cough: an update.
MedLine Citation:
PMID:  24079681     Owner:  NLM     Status:  MEDLINE    
Cough persisting beyond 8 weeks (ie, chronic cough) is one of the most common reasons for an outpatient visit. A protracted cough can negatively affect one's quality of life by causing anxiety, physical discomfort, social isolation, and personal embarrassment. Herein, the anatomy and physiology of the cough reflex are reviewed. Upper airway cough syndrome, asthma, eosinophilic bronchitis, and gastroesophageal reflux disease account for most chronic cough after excluding smoking, angiotensin-converting enzyme inhibitor use, and chronic bronchitis. Many patients have more than one reason for chronic cough. Treating the underlying cause(s) resolves cough in most instances. There are some coughs that seem refractory despite an extensive work-up. The possibility of a hypersensitive cough reflex response has been proposed to explain these cases. Several clinical algorithms to evaluate chronic cough are presented.
Vivek N Iyer; Kaiser G Lim
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Mayo Clinic proceedings     Volume:  88     ISSN:  1942-5546     ISO Abbreviation:  Mayo Clin. Proc.     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-10-01     Completed Date:  2013-12-11     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  0405543     Medline TA:  Mayo Clin Proc     Country:  England    
Other Details:
Languages:  eng     Pagination:  1115-26     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2013 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
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MeSH Terms
Administration, Inhalation
Adrenal Cortex Hormones / administration & dosage*,  therapeutic use
Cough* / drug therapy,  epidemiology,  etiology
Drug-Related Side Effects and Adverse Reactions
Esophageal Diseases / complications*
Gastroesophageal Reflux / complications
Infection / complications*
Respiratory Tract Diseases / complications*
Risk Factors
Reg. No./Substance:
0/Adrenal Cortex Hormones

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