Document Detail

Chromosome mapping of the CYC7 gene determining yeast iso-2-cytochrome c: structural and regulatory regions.
MedLine Citation:
PMID:  206899     Owner:  NLM     Status:  MEDLINE    
The primary structures of iso-1-cytochrome c and iso-2-cytochrome c in the yeast Saccharomyces cerevisiae are determined by the genes CYC1 and CYC7, respectively. The CYC1 locus was previously shown to be on the right arm of chromosome X, and the CYC7 locus is shown in this investigation to be on the left arm of chromosome V closely linked to the min1 and mak10 markers. The CYC7 locus appears to be composed of a structural region and a regulatory region. Mutations in the structural region can cause a deficiency or alteration of iso-2-cytochrome c, whereas mutations in the regulatory region can cause increases in the amount of iso-2-cytochrome c. Single-site gene conversion, occurring at a relatively high frequency of approximately 4%, caused intragenic recombination of a mutational site in the structural region and a mutational site in the regulatory region, enabling us to suggest the order of the sites in relationship to other markers on the chromosome.
F Sherman; J W Stewart; C Helms; J A Downie
Related Documents :
14713029 - Examination of the responses of slimy sculpin (cottus cognatus) and white sucker (catos...
24419509 - Chromosomal control of non-gliadin proteins from the 70% ethanol extract of wheat endos...
6620329 - Fragile x trait in a large kindred: transmission also through normal males.
3460959 - Familial fragile site found at the cancer breakpoint (1)(q32). inducibility by distamyc...
3063949 - Packaging of transducing dna by bacteriophage p1.
3742859 - A family with craniofrontonasal dysplasia, and fragile site 12q13 segregating independe...
6815439 - Does the x chromosome have a special role in immune biology?
17873519 - Take your "m" time.
12838569 - Complete androgen insensitivity syndrome due to x chromosome inversion: a clinical report.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Proceedings of the National Academy of Sciences of the United States of America     Volume:  75     ISSN:  0027-8424     ISO Abbreviation:  Proc. Natl. Acad. Sci. U.S.A.     Publication Date:  1978 Mar 
Date Detail:
Created Date:  1978-07-15     Completed Date:  1978-07-15     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  7505876     Medline TA:  Proc Natl Acad Sci U S A     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1437-41     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Chromosome Mapping
Cytochrome c Group / genetics*,  metabolism
Genes, Regulator*
Linkage (Genetics)
Saccharomyces cerevisiae / genetics*
Reg. No./Substance:
0/Cytochrome c Group

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Human placental cells transformed by tsA mutants of simian virus 40: a model system for the study of...
Next Document:  Transfection of Fv-1 permissive and restrictive mouse cells with integrated DNA of murine leukemia v...