Document Detail


Chromosome location of four genes in Leishmania.
MedLine Citation:
PMID:  3785294     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chromosome-sized DNA molecules from Leishmania isolates (L. mexicana amazonensis, L. mexicana mexicana, L. chagasi, L. major, L. donovani, and L. braziliensis) were separated by orthogonal field alternation gel electrophoresis. The chromosome locations of four genes were mapped. The alpha-tubulin and rRNA genes each mapped to a single chromosome size class. The beta-tubulin and the 5'-spliced-leader-sequence genes were found on more than one chromosome size class and showed variation of hybridization profiles across species.
Authors:
A M Comeau; S I Miller; D F Wirth
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Molecular and biochemical parasitology     Volume:  21     ISSN:  0166-6851     ISO Abbreviation:  Mol. Biochem. Parasitol.     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1987-01-16     Completed Date:  1987-01-16     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8006324     Medline TA:  Mol Biochem Parasitol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  161-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Chromosome Mapping
DNA / analysis
Electrophoresis, Agar Gel
Genes*
Karyotyping
Leishmania / genetics*
Leishmania braziliensis / genetics
Leishmania donovani / genetics
Leishmania mexicana / genetics
Leishmania tropica / genetics
Nucleic Acid Hybridization
Protein Biosynthesis
RNA, Ribosomal / genetics
Species Specificity
Tubulin / genetics
Grant Support
ID/Acronym/Agency:
AI07243/AI/NIAID NIH HHS; AI21365/AI/NIAID NIH HHS; AI22794/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/RNA, Ribosomal; 0/Tubulin; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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