Document Detail


Chromosome-length polymorphism in fungi.
MedLine Citation:
PMID:  8531892     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The examination of fungal chromosomes by pulsed-field gel electrophoresis has revealed that length polymorphism is widespread in both sexual and asexual species. This review summarizes characteristics of fungal chromosome-length polymorphism and possible mitotic and meiotic mechanisms of chromosome length change. Most fungal chromosome-length polymorphisms are currently uncharacterized with respect to content and origin. However, it is clear that long tandem repeats, such as tracts of rRNA genes, are frequently variable in length and that other chromosomal rearrangements are suppressed during normal mitotic growth. Dispensable chromosomes and dispensable chromosome regions, which have been well documented for some fungi, also contribute to the variability of the fungal karyotype. For sexual species, meiotic recombination increases the overall karyotypic variability in a population while suppressing genetic translocations. The range of karyotypes observed in fungi indicates that many karyotypic changes may be genetically neutral, at least under some conditions. In addition, new linkage combinations of genes may also be advantageous in allowing adaptation of fungi to new environments.
Authors:
M E Zolan
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Microbiological reviews     Volume:  59     ISSN:  0146-0749     ISO Abbreviation:  Microbiol. Rev.     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-01-30     Completed Date:  1996-01-30     Revised Date:  2010-09-13    
Medline Journal Info:
Nlm Unique ID:  7806086     Medline TA:  Microbiol Rev     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  686-98     Citation Subset:  IM    
Affiliation:
Department of Biology, Indiana University, Bloomington 47405, USA.
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MeSH Terms
Descriptor/Qualifier:
Chromosomes, Fungal / genetics*
Fungi / genetics*
Karyotyping
Meiosis
Mitosis
Polymorphism, Genetic / genetics*
Grant Support
ID/Acronym/Agency:
GM43930/GM/NIGMS NIH HHS
Comments/Corrections

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