Document Detail


Chromosomal mosaicism in the Killian/Teschler-Nicola syndrome.
MedLine Citation:
PMID:  3740095     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a patient with the Killian/Teschler-Nicola/Pallister mosaic syndrome in association with a cytogenetic abnormality. This patient is the first reported to have lymphocyte mosaicism for an isochromosome of 12p. All other patients with the Killian syndrome have had normal lymphocyte karyotypes, although mosaicism for a similar isochromosome of 12p has been reported in the fibroblasts of most patients with the Killian syndrome.
Authors:
L J Raffel; T Mohandas; D L Rimoin
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of medical genetics     Volume:  24     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1986 Aug 
Date Detail:
Created Date:  1986-09-17     Completed Date:  1986-09-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  607-11     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / genetics*
Alopecia / genetics
Chromosome Aberrations / genetics*
Chromosome Disorders
Chromosomes, Human, 6-12 and X / ultrastructure*
Face / abnormalities
Female
Humans
Infant, Newborn
Mental Retardation / genetics*
Mosaicism*
Phenotype
Syndrome
Grant Support
ID/Acronym/Agency:
GM 07414/GM/NIGMS NIH HHS; HD 19966/HD/NICHD NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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