Document Detail

Chromosomal alterations in peripheral lymphocytes of female cabin attendants.
MedLine Citation:
PMID:  10489894     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To analyse lymphocyte chromosomes from female cabin attendants flying the North Atlantic route. MATERIALS AND METHODS: Peripheral lymphocytes from 58 cabin attendants and 29 controls, all female, were cultured and analyzed for structural chromosomal aberrations and sister chromatid exchanges (SCE). Cytogenetic data from 56 age-matched females from Berlin investigated between 1994 and 1996 as part of routine medical checks were used as an additional control group. RESULTS: The mean frequencies of dicentric and ring chromosomes per 1000 cells amount to 1.3+/-0.2 in cabin attendants, 1.4+/-0.2 in ground personnel and 1.3+/-0.2 in the Berlin control group. Sister chromatid exchanges were found at mean frequencies of 7.0+/-0.1, 6.8+/-0.1 and 6.8+/-0.2 per cell respectively in the three groups. CONCLUSIONS: When compared with controls, cabin attendants have no elevation of the frequencies of dicentric and ring chromosomes and SCE.
G Wolf; R Pieper; G Obe
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of radiation biology     Volume:  75     ISSN:  0955-3002     ISO Abbreviation:  Int. J. Radiat. Biol.     Publication Date:  1999 Jul 
Date Detail:
Created Date:  1999-09-28     Completed Date:  1999-09-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8809243     Medline TA:  Int J Radiat Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  829-36     Citation Subset:  IM; S    
Robert Koch Institut Berlin, Centre of Gene Technology, Germany.
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MeSH Terms
Case-Control Studies
Chromosome Aberrations*
Middle Aged
Occupational Exposure*
Ring Chromosomes
Sister Chromatid Exchange / radiation effects

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