Document Detail

Chromosomal abnormalities in T-cell malignant lymphoma.
MedLine Citation:
PMID:  2054527     Owner:  NLM     Status:  MEDLINE    
Chromosomal abnormalities of T-cell malignant lymphoma are nonrandom and often complex. Some are common with those of other lymphomas, others are more characteristic for T-cell proliferations. The most frequent chromosomal breakpoints involve chromosomes 6, 1, 2, 9p, 17, and the bands where the TcR genes are localized. The frequent rearrangement of band 14q32 suggests that an oncogene is located within. The main results of molecular studies performed in T-cell malignant lymphomas are summarized.
R Berger
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Bulletin du cancer     Volume:  78     ISSN:  0007-4551     ISO Abbreviation:  Bull Cancer     Publication Date:  1991  
Date Detail:
Created Date:  1991-07-30     Completed Date:  1991-07-30     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0072416     Medline TA:  Bull Cancer     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  283-90     Citation Subset:  IM    
Unité INSERM U 301, Institut de Génétique Moléculaire, Paris, France.
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MeSH Terms
Chromosome Aberrations / genetics*
Chromosome Disorders
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 2
Chromosomes, Human, Pair 6
Chromosomes, Human, Pair 9
Gene Rearrangement, T-Lymphocyte / genetics
Lymphoma, T-Cell / complications*,  genetics

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