Document Detail


Chromoblastomycosis associated with Fonsecaea pedrosoi in a carpenter handling exotic woods.
MedLine Citation:
PMID:  18700112     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chromoblastomycosis is a rare, hard to diagnose disease that arises mostly in the tropics, especially in humid areas, affecting mainly males and rural workers. It is characterized by verrucous plaques or nodules that are slow growing and attributed to infection by different pigmented (dematiaceous) fungi. Usually the infection develops after injury, being primarily located on the lower extremities. The authors present the case of a healthy, 60-year-old man observed with a one year history of an erythematous violaceous 5cm tumor located on the right thigh. A biopsy specimen for histopathology revealed single or clustered brown pigmented cells, with a single or double septum and thick cell walls. Cultural smears showed growth of Fonsecaea Pedrosoi. The patient was treated with oral itraconazole (200mg per day), with a good response and clinical cure in 6 months that left only an atrophic scar.
Authors:
Nuno Menezes; Paulo Varela; Antónia Furtado; Antonio Couceiro; Ismália Calheiros; Laura Rosado; Gioconda Mota; Armando Baptista
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-02-28
Journal Detail:
Title:  Dermatology online journal     Volume:  14     ISSN:  1087-2108     ISO Abbreviation:  Dermatol. Online J.     Publication Date:  2008  
Date Detail:
Created Date:  2008-08-13     Completed Date:  2008-10-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610776     Medline TA:  Dermatol Online J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  9     Citation Subset:  IM    
Affiliation:
Serviço de Dermatologia do Centro Hospitalar V.N. de Gaia (CHVNG), Portugal.
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MeSH Terms
Descriptor/Qualifier:
Antifungal Agents / therapeutic use
Ascomycota / isolation & purification
Chromoblastomycosis / diagnosis,  drug therapy,  etiology*,  microbiology
Humans
Itraconazole / therapeutic use
Male
Middle Aged
Mitosporic Fungi / isolation & purification
Occupational Diseases / diagnosis,  drug therapy,  etiology*,  microbiology
Portugal
Thigh
Wood / microbiology*
Chemical
Reg. No./Substance:
0/Antifungal Agents; 84625-61-6/Itraconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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