Document Detail


Chromium and manganese levels in the scalp hair of normals and patients with breast cancer.
MedLine Citation:
PMID:  15621924     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The adverse health effects linked with chromium and manganese and the diverse cellular and molecular effects of chromium and manganese make the study of chromium and manganese carcinogenesis and toxicology very interesting and complex. Quantitative elemental analysis of scalp hair of breast cancer patients (stage III) (n=26) and controls (n=27) were used to study to find correlation and possible changes between breast cancer and healthy controls. The graphite furnace atomic absorption analysis of quantitative method was used for the determination of chromium and manganese element levels. Comparison of mean elemental contents of the breast cancer patients with controls shows a significant enhancement of chromium (p<0.05) but declining trends for manganese (p<0.05) in breast cancer patients. Changes in element content in hair can serve as a guide to opening up new vistas in the treatment of breast cancer on the basis of an overall analysis of symptoms and signs.
Authors:
Eser Kilic; Recep Saraymen; Asuman Demiroglu; Engin Ok
Related Documents :
23249204 - Moving forward in bladder cancer detection and diagnosis: the role of epigenetic biomar...
24212614 - Vitamin d and pancreatic cancer-an update.
11212454 - Audit of referral practice to a fast-access breast clinic before the guaranteed 2-week ...
23950924 - Early experience after developing a pathology laboratory in malawi, with emphasis on ca...
16770654 - Mr colonography: current status.
17287334 - Epidemiologic analysis of reactivated cytomegalovirus antigenemia in patients with cancer.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biological trace element research     Volume:  102     ISSN:  0163-4984     ISO Abbreviation:  Biol Trace Elem Res     Publication Date:  2004  
Date Detail:
Created Date:  2004-12-28     Completed Date:  2005-06-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7911509     Medline TA:  Biol Trace Elem Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  19-25     Citation Subset:  IM    
Affiliation:
Department of Biochemistry and Clinical Biochemistry, Erciyes University, 38039-Kayseri, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Breast Neoplasms / metabolism*,  pathology
Chromium / analysis*
Female
Hair / chemistry*
Humans
Manganese / analysis*
Middle Aged
Neoplasm Staging
Scalp
Chemical
Reg. No./Substance:
7439-96-5/Manganese; 7440-47-3/Chromium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Relationship among manganese, arginase, and nitric oxide in childhood asthma.
Next Document:  Distribution of lead in human milk fractions: relationship with essential minerals and maternal bloo...