| Chromatographic methods for tetracycline analysis in foods. | |
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MedLine Citation:
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PMID: 1494005 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The tetracyclines have served for decades as an important class of antibiotics in food animal health and production. As such, they have also been a source of concern for residue monitoring authorities around the world. In response to this concern a number of microbial inhibition, immunoassay and bacterial receptor methods have evolved for the detection of this class of compounds in various foods of animal origin. However, these methods often lack specificity and are subject to false positive and false negative results. For these reasons a number of chromatographic methods for the separation and determination of the tetracyclines isolated from foods have been developed that are capable of identifying and quantifying individual tetracycline drugs. We present here an overview of tetracycline analytical methods, including microbial inhibition, immunoassay and receptor technologies for detection, techniques for isolation from food matrices, and thin-layer chromatographic, high-performance liquid chromatographic, gas chromatographic and mass spectrometric procedures for determination of this class of compounds. A discussion of the variables involved in such methodology and a review of method criteria are offered. |
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Authors:
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S A Barker; C C Walker |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of chromatography Volume: 624 ISSN: 0021-9673 ISO Abbreviation: J. Chromatogr. Publication Date: 1992 Oct |
Date Detail:
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Created Date: 1993-03-11 Completed Date: 1993-03-11 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0427043 Medline TA: J Chromatogr Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 195-209 Citation Subset: IM |
Affiliation:
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Laboratory for Residue Studies, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Chromatography / methods* Food Analysis* Tetracycline / analysis*, isolation & purification |
| Chemical | |
Reg. No./Substance:
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60-54-8/Tetracycline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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