Document Detail


Chromatographic investigation of macromolecular affinity interactions.
MedLine Citation:
PMID:  15782953     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
High-performance monolithic disk affinity chromatography was applied to the investigation of formation of complexes between (1) complementary polyriboadenylic and polyribouridylic acids, e.g. poly(A) and poly(U), respectively, (2) poly(A) and synthetic polycation poly(allylamine), pAA. Polyriboadenylic acid and poly(allylamine) were immobilized on macroporous disks (CIM disks). Quantitative parameters of affinity interactions between macromolecules were established using frontal analysis at different flow rates.
Authors:
Galina A Platonova; Tatiana B Tennikova
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of chromatography. A     Volume:  1065     ISSN:  0021-9673     ISO Abbreviation:  J Chromatogr A     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-03-23     Completed Date:  2005-07-08     Revised Date:  2009-01-15    
Medline Journal Info:
Nlm Unique ID:  9318488     Medline TA:  J Chromatogr A     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  75-81     Citation Subset:  IM    
Affiliation:
Institute of Macromolecular Compounds, Russian Academy of Sciences, St Petersburg 199004, Russia.
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MeSH Terms
Descriptor/Qualifier:
Adsorption
Chromatography, Affinity / methods*
Chromatography, High Pressure Liquid / methods*
Kinetics
Poly A / chemistry*
Poly U / chemistry*
Chemical
Reg. No./Substance:
24937-83-5/Poly A; 27416-86-0/Poly U

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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