| Choroidal neovascularization with granulomatous inflammation in ocular histoplasmosis syndrome. | |
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MedLine Citation:
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PMID: 11004309 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To report pathologic examination of an excised choroidal neovascular membrane in a patient with ocular histoplasmosis syndrome that demonstrated granulomatous inflammation. METHOD: Case report. A 50-year-old woman with sudden vision loss in her left eye demonstrated clinical and fluorescein angiographic findings characteristic of choroidal neovascularization secondary to ocular histoplasmosis syndrome. RESULTS: Histopathologic examination of the surgically excised choroidal neovascular membrane disclosed granulomatous inflammation. CONCLUSIONS: This case suggests an important role of mononuclear phagocytic cells as primary mediators of angiogenesis or modifiers of choroidal neovascularization. This association of choroidal neovascularization with granulomatous inflammation did not respond to treatment with systemic corticosteroids. |
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Authors:
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E S Mann; S J Fogarty; M C Kincaid |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of ophthalmology Volume: 130 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 2000 Aug |
Date Detail:
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Created Date: 2000-10-26 Completed Date: 2000-11-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 247-50 Citation Subset: AIM; IM |
Affiliation:
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Department of Ophthalmology, Saint Louis University Health Sciences Center, St Louis, Missouri, USA. manne4@slu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Choroidal Neovascularization
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microbiology,
pathology*,
surgery Epiretinal Membrane / microbiology, pathology, surgery Eye Infections, Fungal / microbiology, pathology*, surgery Female Fluorescein Angiography Fundus Oculi Granuloma / microbiology, pathology*, surgery Histoplasmosis / microbiology, pathology*, surgery Humans Middle Aged Syndrome Visual Acuity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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