Document Detail


Choroidal lymphoma masquerading as anterior ischemic optic neuropathy.
MedLine Citation:
PMID:  20306446     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To report a patient with presumed nonarteritic anterior ischemic optic neuropathy (NAION) found on our evaluation to have bilateral uveal lymphoma. METHODS: The clinical history and physical examination, Humphrey visual field testing, ultrasonography, magnetic resonance imaging (MRI), and fine needle aspiration biopsy specimen of a 60-year-old man with presumed NAION were evaluated. RESULTS: The patient initially presented with painless blurred vision OD and foreign body sensation OS. Upon examination, he was found to have optic nerve edema OD suspicious for NAION and oral steroids were employed with no improvement. Later, an abnormality in the left eye raised suspicion for choroidal metastasis. By ultrasound, the tumor in the left choroid was acoustically hollow. MRI of the orbits revealed a choroidal infiltrative process OU. Fine needle aspiration biopsy of OS confirmed atypical lymphocytes, predominantly small to intermediate sized, without necrosis. The patient was treated with external beam radiation therapy to both eyes. CONCLUSIONS: Choroidal lymphoma may present with clinical features of anterior ischemic optic neuropathy or choroidal metastasis.
Authors:
Ali Tavallali; Carol L Shields; Carlos Bianciotto; Jerry A Shields
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  20     ISSN:  1724-6016     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    2010 Sep-Oct
Date Detail:
Created Date:  2010-08-02     Completed Date:  2010-10-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  959-62     Citation Subset:  IM    
Affiliation:
Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA 19107, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Choroid Neoplasms / diagnosis*,  radiotherapy
Diagnosis, Differential
Humans
Lymphoma / diagnosis*,  radiotherapy
Male
Middle Aged
Optic Neuropathy, Ischemic / diagnosis*
Papilledema / diagnosis
Retinal Hemorrhage / diagnosis
Vision Disorders / diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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