Document Detail

Choroidal infarction after photodynamic therapy combined with bevacizumab and triamcinolone reversed by tissue plasminogen activator: case report.
MedLine Citation:
PMID:  25390522     Owner:  NLM     Status:  In-Data-Review    
PURPOSE: To present a case of choroidal infarction after combined therapy of photodynamic therapy, intravitreal bevacizumab, and sub-Tenon triamcinolone injection salvaged by tissue plasminogen activator administration.
METHODS: Interventional case report.
RESULTS: Combined therapy of full-fluence photodynamic therapy, intravitreal bevacizumab, and sub-Tenon triamcinolone injection was given on the same day to treat neovascular age-related macular degeneration in an 82-year-old patient. Subsequent acute visual loss and marked macular edema as a result of choroidal infarction were noted. Intravitreal and sub-Tenon administration of tissue plasminogen activator were performed 9 days later to salvage the choroidal infarction, and visual improvement was noted. Fundoscopy and optical coherent tomography showed almost complete resolution of macular edema. Indocyanine green angiography revealed reperfusion of the choroidal vessels.
CONCLUSION: Choroidal infarction may happen after combined therapy. Tissue plasminogen activator administration may reverse the infarction and help visual recovery.
San-Ni Chen; Chun-Ju Lin; Kun-Hsien Li; Jiunn-Feng Hwang
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Retinal cases & brief reports     Volume:  7     ISSN:  1937-1578     ISO Abbreviation:  Retin Cases Brief Rep     Publication Date:  2013  
Date Detail:
Created Date:  2014-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101298744     Medline TA:  Retin Cases Brief Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  52-6     Citation Subset:  IM    
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