| Choroidal calcifications in patients with Gitelman's syndrome. | |
| | |
MedLine Citation:
|
PMID: 11007691 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Gitelman's syndrome is a renal tubular disorder characterized by a sodium and chloride reabsorption defect in distal tubular cells that determines hypokalemia, metabolic alkalosis, hypomagnesemia, and low calcium excretion. The presence of choroidal calcifications was sought in five patients with Gitelman's syndrome by ophthalmic examination, fluorescein angiography, indocyanine green angiography, and ocular ultrasonography. Calcifications observed in the choroid of two patients were shown by ultrasonography in both patients. Ophthalmic and fluorangiographic examinations detected this alteration in one of the two subjects. Chondrocalcinosis was found in one patient with choroidal calcifications. These findings suggest that precipitation of calcium salts can occur in the choroidal tissue of patients with Gitelman's syndrome. Deposits appeared to be well seen by ultrasonography because of their depth in ocular tissues. Sclerochoroidal calcifications may be favored by the low calcium excretion, which is associated with normal intestinal calcium absorption in patients with Gitelman's syndrome. |
| | |
Authors:
|
G Vezzoli; L Soldati; A Jansen; L Pierro |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: American journal of kidney diseases : the official journal of the National Kidney Foundation Volume: 36 ISSN: 1523-6838 ISO Abbreviation: Am. J. Kidney Dis. Publication Date: 2000 Oct |
Date Detail:
|
Created Date: 2000-10-13 Completed Date: 2000-10-13 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8110075 Medline TA: Am J Kidney Dis Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 855-8 Citation Subset: IM |
Affiliation:
|
Divisions of Nephrology, Dialysis, and Hypertension and Ophthalmology, San Raffaele Scientific Institute, University of Milan, Italy. vezzoli.giuseppe@hsr.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Alkalosis / pathology Calcinosis / pathology*, ultrasonography Choroid / pathology*, ultrasonography Female Humans Hypokalemia / pathology Kidney Diseases / metabolism, pathology* Kidney Tubules / metabolism, pathology* Magnesium / blood, urine Male Middle Aged Potassium / urine Syndrome |
| Chemical | |
Reg. No./Substance:
|
7439-95-4/Magnesium; 7440-09-7/Potassium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Endocapillary proliferative glomerulonephritis in a patient with parvovirus B19 infection.
Next Document: Pauci-immune ANCA-positive crescentic glomerulonephritis associated with metastatic adenocarcinoma o...