Document Detail

Chorioretinitis as a possible very early manifestation of subacute sclerosing panencephalitis.
MedLine Citation:
PMID:  1953517     Owner:  NLM     Status:  MEDLINE    
Ocular changes occur in up to 50% of cases of subacute sclerosing panencephalitis (SSPE) usually at the same time as other neurological signs. Occasionally, visual symptoms precede other manifestations by a few weeks or months. Fundal changes (most commonly a macular chorioretinitis) are the most frequent ocular manifestation of SSPE. Inclusion bodies occur in the retina of patients with chorioretinitis and SSPE and it is believed that the lesions are due to actual viral invasion. We report a case of SSPE in which an atypical chorioretinitis preceded the onset of the typical clinical features of the disease by almost two years. Our case is unusual because of the long interval between the visual symptoms and the onset of other features of SSPE. We wish to emphasise the importance of thinking of SSPE in cases of chorioretinitis which are atypical or occur in young patients. Although treatment of SSPE thus far has been mostly disappointing, earlier diagnosis may offer the hope of better results.
A S Zagami; A K Lethlean
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Australian and New Zealand journal of medicine     Volume:  21     ISSN:  0004-8291     ISO Abbreviation:  Aust N Z J Med     Publication Date:  1991 Jun 
Date Detail:
Created Date:  1991-11-27     Completed Date:  1991-11-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1264322     Medline TA:  Aust N Z J Med     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  350-2     Citation Subset:  IM    
Department of Neurology, Prince Henry Hospital, Australia.
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MeSH Terms
Chorioretinitis / etiology*
Subacute Sclerosing Panencephalitis / complications*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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