Document Detail


Chorion villosum does not express progesterone and estrogen receptors during the first trimester of pregnancy.
MedLine Citation:
PMID:  8878708     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
First-trimester chorion villosum plays the key role in the development of human placenta and secretes a large number of hormones and hormone-related substances. To test whether progesterone and estrogen could have regulatory effects on first-trimester chorion villosum functions, we investigated the presence of progesterone receptor (PR) and estrogen receptor (ER) in 47 chorion villosum samples from patients who underwent abortion during the first trimester of pregnancy. The study was carried out using immunohistochemical methods. No ER and PR positivity was evidenced in the 47 chorion villosum samples examined. The possibility that progesterone and estrogen play a role in the regulation of chorion villosum functions should therefore be excluded.
Authors:
G Taddei; I Noei; E Periti; P Borri; F Torricelli; P Tozzi; D Moncini; M Paglierani; F Branconi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  42     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  1996  
Date Detail:
Created Date:  1997-01-28     Completed Date:  1997-01-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  77-9     Citation Subset:  IM    
Affiliation:
Department of Pathology, University of Florence, Italy.
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Monoclonal / immunology
Chorionic Villi / immunology,  metabolism*
Chorionic Villi Sampling
Female
Humans
Immunohistochemistry
Pregnancy
Pregnancy Trimester, First
Receptors, Estrogen / analysis*,  immunology
Receptors, Progesterone / analysis*,  immunology
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Receptors, Estrogen; 0/Receptors, Progesterone

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