Document Detail


Chorioamnionitis and fetal/neonatal brain injury.
MedLine Citation:
PMID:  11275651     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chorioamnionitis (CA) is the leading cause of preterm birth and neonatal complications. Even in the absence of a proven infection, fetuses and neonates present a systemic inflammatory response which can be identified by radiological and morphological examination of the thymus. The frequent occurrence of brain injury in neonates with CA is probably linked to systemic, unspecific mechanisms which have not yet been completely clarified. Only by relating placental pathology to clinical evaluation of the newborn will it be possible to achieve a better understanding of these infections and to reduce long-term morbidity and mortality.
Authors:
P Toti; C De Felice
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Biology of the neonate     Volume:  79     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  2001  
Date Detail:
Created Date:  2001-03-29     Completed Date:  2001-07-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  201-4     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Affiliation:
Institute of Pathology and Department of Preventive Pediatrics and Neonatology, University of Siena, Italy. paolot@unisi.it
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MeSH Terms
Descriptor/Qualifier:
Brain Diseases / etiology*
Chorioamnionitis / complications*,  pathology
Female
Fetal Death / etiology
Humans
Infant, Newborn
Obstetric Labor, Premature / etiology
Pregnancy
Pregnancy Complications, Infectious

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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