Document Detail

Chorioamnionitis associated with Crohn's disease and azathioprine treatment: a case report.
MedLine Citation:
PMID:  16014435     Owner:  NLM     Status:  MEDLINE    
This paper reports a case of S. constellatus chorioamnionitis in a pregnant Crohn's disease patient who was taking azathioprine. Chorioamnionitis is a major cause of perinatal morbidity. Azathioprine, an immunosuppressive antimetabolite, is widely used to treat inflammatory bowel disease. Streptococcus constellatus is a Gram-positive bacterium that has not previously been associated with chorioamnionitis. A high index of suspicion for chorioamnionitis and unusual pathogens should be maintained in the management of obstetric patients on immunosuppressive agents.
Limor Helpman; David Pauzner; Joseph B Lessing; Michael J Kupferminc; Guy Gutman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of medical microbiology     Volume:  54     ISSN:  0022-2615     ISO Abbreviation:  J. Med. Microbiol.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-07-14     Completed Date:  2005-09-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0224131     Medline TA:  J Med Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  803-4     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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MeSH Terms
Azathioprine / administration & dosage,  adverse effects,  therapeutic use*
Chorioamnionitis / complications,  drug therapy*
Crohn Disease / complications,  drug therapy*,  pathology
Treatment Outcome
Reg. No./Substance:

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