Document Detail

Chorea as a symptom of neuroborreliosis: a case study.
MedLine Citation:
PMID:  10933464     Owner:  NLM     Status:  MEDLINE    
Borrelia burgdorferi (Bb) can cause a large number of neurological symptoms. Although extrapyramidal disturbances are rare (representing less than 2% of all neurological complications), diffuse choreic dyskinesias have been described during the course of mild encephalitis. The data published in the literature suggest that there are clinical and neurological analogies between neuroborreliosis and multiple sclerosis (MS). The presence of specific anti-Bb antibodies in cerebrospinal fluid is a discriminating factor that allows a diagnosis of neuroborreliosis to be made. We describe the case of a patient with Lyme disease, characterised by widespread chorea and behavioural disturbances. Emphasis is placed on the atypical onset and evolution, the difficulties encountered in formulating a diagnosis, and the uncertainties concerning the pathophysiology and clinical/neuroradiological correlations of the disease.
I Piccolo; G Thiella; R Sterzi; N Colombo; C A Defanti
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Italian journal of neurological sciences     Volume:  19     ISSN:  0392-0461     ISO Abbreviation:  Ital J Neurol Sci     Publication Date:  1998 Aug 
Date Detail:
Created Date:  2000-08-29     Completed Date:  2000-08-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8006502     Medline TA:  Ital J Neurol Sci     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  235-9     Citation Subset:  IM    
Division of Neurology, Hospital Niguarda Ca' Granda, Milan, Italy.
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MeSH Terms
Brain / pathology
Chorea / microbiology*,  pathology*
Lyme Neuroborreliosis / complications*,  pathology*
Magnetic Resonance Imaging
Middle Aged

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