Document Detail

Chordae tendineae rupture resulting in pulmonary edema in a patient with discrete subvalvular aortic stenosis--a case report and literature review.
MedLine Citation:
PMID:  14565639     Owner:  NLM     Status:  MEDLINE    
This report concerns an apparently healthy elderly woman who presented with gradually worsening mitral regurgitation secondary to chordae tendineae rupture leading to pulmonary edema in the presence of discrete subvalvular aortic stenosis with a severe gradient reflecting the left ventricular outflow tract obstruction. The gradual worsening of heart failure took place parallel to the increase in severity of mitral regurgitation in a short period. The patient underwent successful mitral valve replacement with myectomy. Surgical inspection revealed rupture of the chordae tendineae to the posterior leaflets without any significant primary intrinsic disease of the mitral valve. The predominant mechanism of chordae tendineae rupture in this patient with discrete subvalvular aortic stenosis is a severe pressure gradient. It is suggested that increased awareness of chordae tendineae rupture as a cause of mitral regurgitation and the prompt use of appropriate diagnostic tools may facilitate the timely recognition of this potentially fatal, but treatable, cause of mitral regurgitation in patients with left ventricular outflow tract obstruction.
O Adler; S Kalidindi; A Butt; K M A Hussain
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Angiology     Volume:  54     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:    2003 Sep-Oct
Date Detail:
Created Date:  2003-10-20     Completed Date:  2003-11-04     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  613-7     Citation Subset:  IM    
Division of Cardiology, Department of Medicine, Conemaugh Memorial Medical Center, Johnstown, PA, USA.
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MeSH Terms
Aortic Stenosis, Subvalvular / complications*
Heart Rupture / complications*
Mitral Valve Insufficiency / etiology
Pulmonary Edema / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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